Calyculin A induces prematurely condensed chromosomes without histone H1 phosphorylation in mammalian G1-phase cells
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چکیده
منابع مشابه
Calyculin A induces prematurely condensed chromosomes without histone H1 phosphorylation in mammalian G1-phase cells
It is shown here that one can induce prematurely condensed chromosomes (PCCs) in G1-phase human (HeLa) and mouse (FT210) cells by treating them with the protein phosphatase inhibitor calyculin A. However, histone H1 is not phosphorylated in these G1-PCCs. It has previously been proposed that histone H1 phosphorylation is responsible for mitotic chromosome condensation, but our results suggest t...
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ژورنال
عنوان ژورنال: Advances in Biological Chemistry
سال: 2013
ISSN: 2162-2183,2162-2191
DOI: 10.4236/abc.2013.33a005